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Tuesday, January 10, 2012
Alarming Incidence of Hepatitis C Virus Re-Infection After Treatment of Sexually Acquired Acute Hepatitis C Virus Infection in HIV-Infected MSM
The subjects of the Amsterdam-based study were HIV-infected MSM attending two large outpatient clinics; the men were previously diagnosed with a sexually transmitted acute HCV infection and tested HCV RNA-negative at the conclusion of treatment. "We defined HCV re-infection as detectable HCV RNA in individuals with an undetectable HCV RNA at the end of treatment accompanied by a switch in HCV genotype or clade," the authors wrote. Re-infection incidence was calculated using person-time methods.